You may be running into the limits of your Mac’s processing power. FreeStyle gives priority to sending and receiving MIDI data over most screen redisplays. However, with enough of an overload you may hear delays or erratic timing in your music.
Usually the overload is caused by vast reams of aftertouch (mono or poly key pressure), controller, or pitch bend events in one or more synthesizer tracks.
To solve the problem, you must reduce the amount of MIDI information being passed through the modem and/or printer port in one of the following ways:
Slow down the tempo of the sequence during the problem passages.
Delete unneeded aftertouch or other controller data in the controller view.